What Are The Pros And Cons Of Chemical Castration?
Some men prefer chemical castration for cosmetic reasons, because they appear normal. Others fear surgery. However, prolonged use of anti-androgen hormones has serious side-effects, so you may opt for surgery. Depo-Provera causes weight gain, drowsiness, depression, high blood pressure (hypertension), and low blood sugar (hypoglycemia). Depo-Provera can cause deadly travelling blood clots (embolism) and liver damage from fatty infiltration of the tissue and changes in enzymes. If you opt for chemical castration, you may need tamoxifen to prevent breast cancer.
Zoladex® (goserelin) side effects in men include: decreased erections, decreased libido, hot flushes, swelling of extremities, nausea, breathlessness, diarrhoea and urinary tract infection.
Compliance is a problem with Depo-Provera®. You must be prepared to take Depo-Provera® or another anti-androgen injection on a weekly basis, and to have monthly blood tests to ensure your male hormones are adequately suppressed. If you stop treatment, your testosterone and sexual function return to normal in 7 to 10 days.
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